Longevity

Top 5 Takeaways from LongevityFest 2024

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Article Summary

LongevityFest 2024 illuminated groundbreaking advancements shaping the future of healthspan and longevity. From cutting-edge research to innovations in personalized medicine, experts are paving the way for optimized aging and enhanced quality of life. Empower Pharmacy, committed to advancing healthcare innovation, is excited to share key insights and our Top 5 Takeaways.

Top 5 Takeaways from LongevityFest 2024

Insights shaping the future of healthspan and longevity, brought to you by Empower Pharmacy.

1. Women and Menopause: A Critical Health Focus

Key Insight: Menopause affects over 1 million U.S. women annually1, with 64 medically recognized symptoms2 including but not limited to hot flashes, weight gain, vaginal dryness, and loss of libido. Personalized options, such as hormone replacement therapy (HRT), could aid in improving the quality of life during this transition.3


Why It Matters: Optimizing hormone balance during menopause may help reduce the risk of osteoporosis4, and may help improve sexual function5, and urogenital health5.

2. The Power of Mitochondria in Healthy Aging

Key Insight: Mitochondria are responsible for over 90% of the body’s energy production6, yet mitochondrial function declines steadily with age7. Improving mitochondrial health could potentially reduce fatigue8 and delay aging-related diseases9.


Why It Matters: Mitochondrial optimization is a critical component for maintaining energy6, immune health10, and longevity9.

3. Cellular Renewal: The Role of Senolytics

Key Insight: Research shows that the accumulation of senescent cells could potentially contribute to chronic inflammation11, immune dysfunction11, and reduction of tissue regeneration1 1. Senolytics can potentially help remove these “zombie cells12 ,” and may potentially aid  in improving healthspan13.


Why It Matters: New research in mice shows that potentially clearing senescent cells may reduce inflammation14 and could potentially improve overall health.

4. Nutrition and Longevity: The Science of Healthspan

Key Insight: Nutrition plays a pivotal role in aging. Studies suggest that healthy eating patterns were associated with a 20% reduction in total mortality as well as a lower risk of mortality due to cardiovascular disease or cancer15 Nutrient supplementation can potentially reduce oxidative stress16 and possibly improve metabolic health16.


Why It Matters: Proper nutritional interventions can potentially slow age-related diseases and improve the quality of life for patients of all ages .

5. Personalized Medicine: The Future of Longevity

Key Insight: Advances in genetic19, epigenome20, and biomarker21 testing are transforming healthcare by enabling fully personalized treatments. These approaches in personalized medicine have the potential to optimize therapies for maximum benefit and minimal side effects22.


Why It Matters: Tailored protocols could potentially enhance the patient treatment plan22 and empower patients to participate actively in their care23.

Why Choose Empower Pharmacy?

Our core belief is to provide access to personalized, affordable medication through innovation with a commitment to quality, service and people.

  • Commitment to Innovation: Our state-of-the-art facilities use advanced technology and equipment to produce high-quality, custom medications at scale through our 503A pharmacy and 503B outsourcing facility.
  • Personalized Medications: Healthcare’s evolving landscape demands diverse treatment options. Tailored to individual needs, we contribute to personalized care and expand the treatment spectrum for patients seeking optimal outcomes.
  • Trusted Partner: To ensure the reliability and quality of our products, our multi-pronged quality process adheres to stringent regulatory standards at every step—from ingredient sourcing to fulfillment—so the medications we send out are of the highest caliber every time.

Conclusion:

The future of longevity and healthspan lies in personalized, innovative approaches to care. By embracing emerging therapies and technologies, healthcare providers can empower patients to lead healthier, more vibrant lives. At Empower Pharmacy, we are proud to play a role in this evolution, offering customizable medication solutions to support cutting-edge healthcare. Together, we can shape a healthier tomorrow.

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*Compounded medications are not approved by the FDA and are not tested by the FDA for safety and efficacy.

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  2. Federation of State Medical Boards. (n.d.). Menopause management: The latest in hormone therapy and beyond [Course]. Retrieved from https://www.pathlms.com/fsmb/courses/80041
  3. National Institute on Aging. (n.d.). What is menopause? National Institutes of Health. Retrieved from https://www.nia.nih.gov/health/menopause/what-menopause
  4. Cleveland Clinic. (n.d.). Osteoporosis and menopause: How they’re connected and what you can do. Retrieved from https://health.clevelandclinic.org/osteoporosis-and-menopause
  5. National Center for Biotechnology Information. (n.d.). Estrogen Therapy. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/sites/books/NBK541051/
  6. National Institutes of Health. (2010, April). When cells face an energy crisis. NIH News in Health. Retrieved from https://newsinhealth.nih.gov/2010/04/when-cells-face-energy-crisis
  7. Chistiakov DA, Sobenin IA, Revin VV, Orekhov AN, Bobryshev YV. Mitochondrial aging and age-related dysfunction of mitochondria. Biomed Res Int. 2014;2014:238463. doi: 10.1155/2014/238463. Epub 2014 Apr 10. PMID: 24818134; PMCID: PMC4003832. https://pmc.ncbi.nlm.nih.gov/articles/PMC4003832/
  8. Nicolson GL. Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements. Integr Med (Encinitas). 2014 Aug;13(4):35-43. PMID: 26770107; PMCID: PMC4566449. https://pmc.ncbi.nlm.nih.gov/articles/PMC4566449/
  9. Srivastava S. The Mitochondrial Basis of Aging and Age-Related Disorders. Genes (Basel). 2017 Dec 19;8(12):398. doi: 10.3390/genes8120398. PMID: 29257072; PMCID: PMC5748716. https://pmc.ncbi.nlm.nih.gov/articles/PMC5748716/
  10. Angajala A, Lim S, Phillips JB, Kim JH, Yates C, You Z, Tan M. Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism. Front Immunol. 2018 Jul 12;9:1605. doi: 10.3389/fimmu.2018.01605. PMID: 30050539; PMCID: PMC6052888. https://pmc.ncbi.nlm.nih.gov/articles/PMC6052888/
  11. Aquino-Martinez R, Eckhardt BA, Rowsey JL, Fraser DG, Khosla S, Farr JN, Monroe DG. Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice. J Periodontol. 2021 Oct;92(10):1483-1495. doi: 10.1002/JPER.20-0529. Epub 2021 Jan 6. PMID: 33341947; PMCID: PMC8281492. https://pmc.ncbi.nlm.nih.gov/articles/PMC8281492/
  12. University of California, San Francisco. (2022, October 13). Senescent cells also help heal damaged tissues. Retrieved from https://www.ucsf.edu/news/2022/10/424041/senescent-cells-also-help-heal-damaged-tissues
  13. Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Senolytics improve physical function and increase lifespan in old age. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. PMID: 29988130; PMCID: PMC6082705. https://pmc.ncbi.nlm.nih.gov/articles/PMC6082705
  14. National Institute on Aging. (n.d.). Cellular therapy targeting senescent cells may improve health in mice. National Institutes of Health. Retrieved from https://www.nia.nih.gov/news/cellular-therapy-targeting-senescent-cells-may-improve-health-mice
  15. American Medical Association. (n.d.). Diet patterns can boost longevity, cut chronic disease. Retrieved from https://www.ama-assn.org/delivering-care/public-health/diet-patterns-can-boost-longevity-cut-chronic-disease
  16. Dama A, Shpati K, Daliu P, Dumur S, Gorica E, Santini A. Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation. Nutrients. 2024 Feb 10;16(4):507. doi: 10.3390/nu16040507. PMID: 38398830; PMCID: PMC10891887. https://pmc.ncbi.nlm.nih.gov/articles/PMC10891887/
  17. Fekete M, Szarvas Z, Fazekas-Pongor V, Feher A, Csipo T, Forrai J, Dosa N, Peterfi A, Lehoczki A, Tarantini S, Varga JT. Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases. Nutrients. 2022 Dec 22;15(1):47. doi: 10.3390/nu15010047. PMID: 36615705; PMCID: PMC9824801. https://pmc.ncbi.nlm.nih.gov/articles/PMC9824801/
  18. Ho D, Quake SR, McCabe ERB, Chng WJ, Chow EK, Ding X, Gelb BD, Ginsburg GS, Hassenstab J, Ho CM, Mobley WC, Nolan GP, Rosen ST, Tan P, Yen Y, Zarrinpar A. Enabling Technologies for Personalized and Precision Medicine. Trends Biotechnol. 2020 May;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021. Epub 2020 Jan 21. PMID: 31980301; PMCID: PMC7924935. https://pmc.ncbi.nlm.nih.gov/articles/PMC7924935/
  19. ational Human Genome Research Institute. (n.d.). Genetic testing. Retrieved from https://www.genome.gov/genetics-glossary/Genetic-Testing
  20. National Human Genome Research Institute. (n.d.). Epigenomics fact sheet. Retrieved from https://www.genome.gov/about-genomics/fact-sheets/Epigenomics-Fact-Sheet
  21. American Cancer Society Cancer Action Network. (n.d.). Access to biomarker testing. Retrieved from https://www.fightcancer.org/what-we-do/access-biomarker-testing
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